subjectId
Discipline Name
Subject Name
Coordinators
Type
Institute
Content
102101003
Biotechnology
Biomathematics
Dr. Ranjith Padinhateeri
Video
IIT Bombay
Select
L1-Introduction
L2-Graphs and functions - I
L3-Graphs and functions - II
L4-Functions and derivatives
L5-Calculation of derivatives
L6-Differentiation and its application in Biology - I
L7-Differentiation and its application in Biology - II
L8-Differentiation and its application in Biology - III
L9-Differentiation and its application in Biology - IV
L10-Integration - I
L11-Integration - II
L12-Differential equations-I
L13-Differential equations - II
L14-Vectors - I
L15-Vectors - II
L16-Vectors - III
L17-Nernst equation
L18-Diffusion-I : Diffusion equation
L19-Diffusion - II: Mean-square displacement
L20-Diffusion-III : Einstein�s relation
L21-Statistics : Mean and variance
L22-Statistics: Distribution function
L23-Understanding Normal distribution
L24-Fitting a function to experimental data
L25-Size of a flexible protein: Simplest model
L26-Uniform and Poisson distributions; Knudson�s analysis
L27-Fourier Series-I
L28-Fourier Series-II
L29-Fourier transform
L30-Master equation: Polymerization dynamics, Molecular motor motion
L31-Evolution: Simplest model
L32-Tutorial - I
L33-Tutorial-II
L34-Temperature, Energy and Entropy
L35-Partition function, Free energy
L36-Bending fluctuations of DNA and spring-like proteins
L37-Force-extension and looping of DNA
L38-Thermodynamics of protein organization along DNA
L39-Learning mathematics with the help of a computer
102101007
Biotechnology
Proteomics: Principles and Techniques
Prof. Sanjeeva Srivastava
Video
IIT Bombay
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VIDEO-L29
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VIDEO-L30
PPT-L30
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VIDEO-L31
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102101040
Biotechnology
Advanced Clinical Proteomics
Prof. Sanjeeva Srivastava
Web
IIT Bombay
Select
LECTURE-L-1
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102102033
Biotechnology
Enzyme Science and Engineering
Prof. Subhash Chand
Video
IIT Delhi
Select
Introduction and Scope to Enzyme Science & Engineering
Characteristic Features of Enzymes
Enzymes as Biocatalysts
Enzymatic Catalysis
Specificity of Enzyme Action
Kinetics of Enzyme Catalyzed Reactions
Kinetics of Enzyme Catalyzed Reactions
Deviation from Hyperbolic Enzyme Kinetics
Role of Effector Molecules in Enzyme Kinetics
Reversible Inhibition
Effect of PH and Temperature on Enzyme
Kinetics of Bi substrate Enzyme
Kinetics of Bi substrate Enzyme
Immobilized Enzymes - I
Immobilized Enzymes - II
Immobilized Enzymes - III
Immobilization of Enzymes by Entrapment
Effect of Immobilization
Reactors for Enzyme Catalyzed Reactions
Idealized Enzyme Reactor Performance
Idealized Enzyme Reactor Performance
Kinetic Parameters for IME Systems
Steady State Analysis of Mass Transfer
Steady State Analysis of Mass Transfer
Non Ideal Flow in Continuous Immobilized Enzyme
Applications of Immobilized Enzymes in Process
Analytical Applications
Enzyme Technology Challenges
102103012
Biotechnology
Cell Biology
Dr. Sanjukta Patra
Web
IIT Guwahati
Select
Prokaryotic and Eukaryotic cells
Plant and animal cells
Principles of membrane organization, membrane proteins
Cytoskeletal elements and architecture
Structure and function of cytoplasm, nucleus and mitochondria
Ribosome, endoplasmic reticulum, golgi bodies and lysosomes
Peroxisomes, chloroplast and vacuoles
Extracellular matrix
Cell locomotion (amoeboid, flagella, cillar)
Types of cell division, Cell cycle and molecules that control cell cycle
Mitosis
Meiosis
Genetic material in a cell
Human Cromosome
Giant chromosomes
Transport across cell membrane
Lactose permease
Lysosomal membrane
ATP dependent proton pumps
Cotransport: Symport, Antiport
Transport in prokaryotic cells
Endocytosis and Exocytosis
Entry of virus in cells
Entry of toxins into the cells
Hormone
Plant growth factors
Plant hormones
Cell signaling
Receptor
Cyclic adenosine monophosphate ( cAMP)
Cyclic Guanosine monophosphate
Calcium ion flux and its role in cell signaling
G � Protein
Cell Culture
Characterization of Cells
Contamination
Differentiation
Three Dimentional Culture
Role of matrix in cell growth
Components of blood plasma cell
Haemopoiesis
102103016
Biotechnology
Plant Biotechnology
Dr. Rakhi Chaturvedi
Web
IIT Guwahati
Select
Introduction to plant tissue culture
Lab facilities and operations
Tissue Culture Media
Plant Tissue culture techniques
Micropropagation by adventitious shoot proliferation
Micropropagation by Axillary shoot proliferation
Meristem culture for virus elimination
Somatic Embryogenesis and Artificial seed production
Doubled Haploid production
Triploid production by Endosperm culture
Cell suspension cultures
Protoplast Isolation and Regeneration
Somatic Hybridization and Cybridization
Somaclonal, Protoclonal and Gametoclonal variation
Cryopreservation
Cytological and various staining procedures for Ploidy analysis
Microscopy
Electron Microscopy
Flow Cytometry and cell sorting
Plant Histological Techniques
Genetic material of plant cells
Restriction Enzymes
Plant transformation and transformation vectors
Mode of Gene delivery in plant
Agrobacterium mediated Gene transfer
Ti and Ri Plasmids
Selection and screening of transformations
PCR and Hybridization technique
Gene silencing
Applications of Genetic Engineering
Advantages of Plant cell, Tissue and organ culture as source of secondary metabolites
Hairy Root cultures
Screening of High yielding cell lines and extraction of High value Industrial Products
Fractionation and Bioassays of plant extract
Growth and Production Kinetics of Cell cultures in Shake Flasks
Bioreactors for Plant Engineering
Manipulation in Production Profile by Abiotic and Biotic Elicitation
Biotransformation
Aims Scope and Bottlenecks of Molecular Farming
Production of Industrial Enzymes and Biodegradable Plastics
Production of Antibodies
Metabolic Engineering for Production of Fatty Acids, Industrial Oils, Terpenoids and Flavonoids
102103017
Biotechnology
Proteomics and Genomics
Dr. Vikash Kumar Dubey
Web
IIT Guwahati
Select
Introduction and Scope of Proteomics
Protein Separation Techniques: General Concepts of Chromatography
Ion Exchange Chromatography-I
Ion Exchange Chromatography �II
Size Exclusion (Gel Filtration) Chromatography
Affinity Chromatography-I
Affinity Chromatography-II
Affinity Chromatography-III
Polyacrylamide Gel Electrophoresis
Polyacrylamide Gel Electrophoresis-II
Isoelectric Focusing (IEF)
Two Dimensional PAGE for Proteome Analysis
Analysis of 2D Gels
Suggested Reading and Home Assignment
Introduction to Mass Spectrometry-I
Introduction to Mass Spectrometry-II
Strategies for Protein Identification
Protein Sequencing
Protein Modifications and Proteomics
Protein-Protein Interaction
Midterm Examination
Protein Engineering
Clinical and Biomedical Applications of Proteomics Proteomics Industry
Protein Chip Technology
Functional Proteomics and Proteome Database
Overview of Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) Structure
Agarose Gel Electrophoresis for DNA Analysis
Methods of Preparing Genomic DNA
DNA Sequence Analysis Methods-I
DNA Sequence Analysis Methods-II
Home Assignment and Further Reading
Gene Variations and Single Nucleotide Polymorphism
Expressed Sequence Tags
DNA & Disease Association
Basics of DNA Cloning-I
Basics of DNA Cloning-II
Polymerase Chain Reaction
DNA Fingerprinting
Human Genome Project
Final Examination
102103038
Biotechnology
Cellular and Molecular Immunology
Dr. Sachin Kumar
Web
IIT Guwahati
Select
Introduction
Properties of Immune system
Innate immune system (Part I)
Innate immune system (Part II).
Adaptive immune system (Part I)
Questions: Introduction
Antibodies and Antigens (Part I)
Antibodies and Antigens (PartII)
Major histocompatability complex (Part I)
Major histocompatability complex (Part II)
Antigen processing and presentation to T lymphocyte (Part I)
Antigen processing and presentation to T lymphocyte (Part II)
Antigen receptors and accessory molecules of T lymphocytes. (Part I)
Antigen receptors and accessory molecules of T lymphocytes. (Part II)
Development of Lymphocytes (Part I)
Development of Lymphocytes (Part II)
Activation of Lymphocytes (Part I)
Activation of Lymphocytes (Part II)
B cell activation and antibody production (Part I)
B cell activation and antibody production (Part II)
Immune memory response (Part I).
Immune memory response (Part II).
Cytokines (Part I
Cytokines (Part II)
Mechanism of cell mediated immune response (Part I)
Mechanism of cell mediated immune response (Part II)
Mechanism of antibody medicated immune response (Part I)
Mechanism of antibody medicated immune response (Part II)
Immunity to microbes (Part I)
Immunity to microbes (Part II)
Transplant immunology (Part I)
Transplant immunology (Part II)
Tumor immunology (Part I)
Tumor immunology (Part II)
Hypersensitivity (Part I)
Hypersensitivity (Part II)
Congenital and acquired immunodeficiency (Part I)
Congenital and acquired immunodeficiency (Part II).
Laboratory techniques commonly used in immunology (Part I)
Laboratory techniques commonly used in immunology (Part II)
Adaptive immune system (Part II)
Questions: Antibodies and Antigens
Questions: Development of immune cells
Questions: Mechanism of immune response
Questions: Immunity to pathogens
Questions: Hypersensitivity and immunodeficiency
Mid Term Assignment
Final Assignment
102103039
Biotechnology
General Virology
Dr. Sachin Kumar
Web
IIT Guwahati
Select
General Concepts: Virus history
General Concepts: Virus Diversity
General Concepts: Virus Shapes
General Concepts: Virus Sizes
General Concepts: Components of genomes.
Isolation and purification of viruses and components.
Questions : General Concepts
Consequences of virus infection to animals and human (Part I).
Consequences of virus infection to animals and human (PartII).
Viral infection: affect on host macromolecules (Part I).
Viral infection: affect on host macromolecules (Part II).
Viral infection: establishment of the antiviral state (Part I).
Viral infection: establishment of the antiviral state (Part II).
Viruses counter attack mechanisms (Part I).
Viruses counter attack mechanisms (Part II)
Classification of viruses and nomenclatures (Part I).
Classification of viruses and nomenclatures (Part II)
Positive strand RNA viruses
Picornaviruses.
Flaviviruses- West Nile virus
Flaviviruses- Dengue virus
Coronaviruses
SARS pathogenesis
Negative strand RNA viruses
Paramyxoviruses
Orthomyxoviruses
Influenza pathogenesis and Bird flu
Rhabdoviruses
Rabies pathogenesis
dsRNA viruses
Reoviruses
Questions: Virus host interaction
Questions: Positive strand RNA virus
Questions: Negative strand RNA viruses
Retroviruses: structure, classification, life cycle
Reverse transcription
HIV- viral pathogenesis
AIDS
Questions: Other RNA viruses
Small DNA viruses: parvo- and polyomaviruses
Large DNA viruses
Herpesviruses
Adenoviruses
Poxviruses
Miscellaneous viruses
Questions: DNA viruses
Mid Term Assignment
Final Assignment
102103041
Biotechnology
Gene Therapy
Dr. Sachin Kumar
Web
IIT Guwahati
Select
Introduction (part I)
Introduction (part II)
Somatic and germ line gene therapy (part I)
Somatic and germ line gene therapy (part II)
Gene replacement and gene addition (part I)
Gene replacement and gene addition (part II)
In vivo, ex vivo and in vitro gene therapy (Part I)
In vivo, ex vivo and in vitro gene therapy (PartII)
Transgenic animal models (Part I)
Transgenic animal models (Part II).
Vehicles for gene transfer-viral vectors: retrovirus (Part I).
Vehicles for gene transfer-viral vectors: retrovirus (Part II).
Adenovirus
Adeno-associated virus.
Lentivirus
Recombinant SV40 virus
Nonviral vectors
DNA vaccines
Liposomes and lipoplexes (Part I).
Liposomes and lipoplexes (Part II).
Naked DNA
Transposon
Cancer gene therapy (Part I).
Cancer gene therapy (Part II).
Cancer gene therapy (Part III).
RNA-DNA chimera
Gene therapies for Criglar-Najjar syndrome (Part I).
Gene therapies for Criglar-Najjar syndrome (Part II).
Cystic fibrosis (part I)
Cystic fibrosis (part II)
Duchnne muscular dystrophy
Bleeding disorders (part I)
Bleeding disorders (part II)
Tyrosinemia
Severe combined immunodeficiency syndrome (SCID) (part I)
Severe combined immunodeficiency syndrome (SCID) (part II)
Gene therapy of non-heritable disorders (part I)
Gene therapy of non-heritable disorders (part II)
Recent advancement in Gene Therapy (part I)
Recent advancement in Gene Therapy (part II)
Mid Sem Exam
Final Sem Exam
Question Set I
Question Set II
Question Set III
Question Set IV
Question Set V
Question Set VI
102103044
Biotechnology
Bioanalytical Techniques and Bioinformatics
Dr. Nitin Chaudhary,Dr. Vishal Trivedi
Web
IIT Guwahati
Select
Introduction (part I)
Introduction (part II)
Somatic and germ line gene therapy (part I)
Somatic and germ line gene therapy (part II)
Gene replacement and gene addition (part I)
Gene replacement and gene addition (part II)
In vivo, ex vivo and in vitro gene therapy (Part I)
In vivo, ex vivo and in vitro gene therapy (PartII)
Transgenic animal models (Part I)
Transgenic animal models (Part II).
Vehicles for gene transfer-viral vectors: retrovirus (Part I).
Vehicles for gene transfer-viral vectors: retrovirus (Part II).
Adenovirus
Adeno-associated virus.
Lentivirus
Recombinant SV40 virus
Nonviral vectors
DNA vaccines
Liposomes and lipoplexes (Part I).
Liposomes and lipoplexes (Part II).
Naked DNA
Transposon
Cancer gene therapy (Part I).
Cancer gene therapy (Part II).
Cancer gene therapy (Part III).
RNA-DNA chimera
Gene therapies for Criglar-Najjar syndrome (Part I).
Gene therapies for Criglar-Najjar syndrome (Part II).
Cystic fibrosis (part I)
Cystic fibrosis (part II)
Duchnne muscular dystrophy
Bleeding disorders (part I)
Bleeding disorders (part II)
Tyrosinemia
Severe combined immunodeficiency syndrome (SCID) (part I)
Severe combined immunodeficiency syndrome (SCID) (part II)
Gene therapy of non-heritable disorders (part I)
Gene therapy of non-heritable disorders (part II)
Recent advancement in Gene Therapy (part I)
Recent advancement in Gene Therapy (part II)
Mid Sem Exam
Final Sem Exam
Question Set I
Question Set II
Question Set III
Question Set IV
Question Set V
Question Set VI
102103045
Biotechnology
Fundamentals of Biotechnology
Dr. Vishal Trivedi
Web
IIT Guwahati
Select
Introduction
Water properties and its role in controlling biochemical reactions
Cellular structure: prokaryotcic and eukaryotic cells (Part-I)
Cellular structure: prokaryotcic and eukaryotic cells(Part-II)
Metabolic reactions (Part-I)
Metabolic reactions (Part-II)
Metabolic reactions (Part-III)
Growth media for different expression system
Microbial growth kinetics
DNA Libaries (PART-I)
DNA Libaries (PART-II)
Identification and Isolation of a particular gene
Basics of Cloning (Part-I)
Basics of Cloning (Part II)
Polymerase chain reaction (Part-I)
Polymerase chain reaction (Part-II)
Cloning Vector (Part-I)
Cloning Vector (Part-II)
Cloning Vector (Part-III)
DNA Delivery in Host Cell (Part-I)
DNA Delivery in Host Cell (Part-II)
Screening of recombinant clone (Part-I)
Screening of recombinant clone (Part II)
Protein Production strategies in Expression System (Part-I)
Protein Production strategies in Expression System (Part-II)
Protein Production strategies in Expression System (Part-III)
Protein Production strategies in Expression System (Part-VI)
Product Recovery from over-expressed cells
Basics of Chromatography
Ion-Exchange chromatography
Hydrophobic Interaction chromatography
Gel Filtration chromatography
Affinity Chromatography
Thin Layer Chromatography
Electrophoresis (Part-I)
Electrophoresis (Part-II)
DNA sequencing
Protein sequencing
Biotechnology Application-I
Biotechnology Application-II
Mid Sem Exam
End Sem Exam
102106023
Biotechnology
Introduction to Computational Neuroscience
Dr. V Srinivasa Chakravarthy
Web
IIT Madras
Select
Introduction
Neuron: Structure and Function
Mathematical Preliminaries
Hodgkin-Huxley Model
Modeling the neuron components
Simplified Neuron Models
Neural Networks
Neural Networks- Hopfield network
Unsupervised Learning-Hebbian Learning
Unsupervised Learning-Competitive Learning
102106026
Biotechnology
Thermodynamics
Prof. G.K. Suraishkumar
Video
IIT Madras
Select
Introduction and Review
Need for Analysis Additional Thermodynamic Functions State and Path Variables
Equations for a Closed system Chemical Potential Concept Gibbs-Duhem Equation
Maxwell�s relations
Inter-Relationships between Thermodynamic Variables
Some Useful Mathematical Manipulations
Thermodynamic Relations for a Closed System with 1 mole of a pure Substances
Maximum Work,Lost Work Review of Closed Systems
Open Systems
Equations of State - Virial Equations
Equations of State - Cubic Equations
Volume Estimation
Volume Estimation (cont.,)Generalized correlations
Generalized correlations(cont)Residual Properties
Residual Properties(cont.,)
Generalized Correlations and Residual Properties
Fugacity Coefficient Estimation
Review of Module 3
Learning Aspects Chemical Potential Formulations
Lewis and Randall rule partial Molar Properties
Partial Molar Property Estimation from Mixing Experiments
Partial Molar Property Estimation (cont.,) Excess Property
Activity Coefficient from Excess Property
Activity Coefficient from Excess Property (cont.,)
Activity Coefficient from Excess Property(cont.,) Models for Activity Coefficient in Binary Systems
Models for Activity Coefficient in Binary Systems(cont.,)
Review of Module 4
Criteria for Phase Equilibrium Phase Rule for Non-reacting Biosystems
Clausius - Clayperon Equation
Clausius - Clayperon Equation(cont.,)vapour-Liquid Equilibrium
Vapour-Liquid Equilibrium(cont.,) Estimation of Fugacity coefficient from Equilibrium P-V-T Data
Liquid/Liquid and Solid/Liquid Equilibria
Review of Module 5
Criteria for Bio-reaction Equilibria
Phase rule for Reacting Biosystems Equilibrium constants
Effect of Temperature and Pressure on the Equilibrium constants
Reaction in Liquid or Solid Phases
Free energy Changes for some Bioreactions
Electrolytes
Course Review
102106035
Biotechnology
Systems Biology
Dr. M. Vijayalakshmi
Web
IIT Madras
Select
Systems Biology � An Overview
Overview of Gene Control
Gene Control Mechanisms at Transcriptional and Translational Levels
Genetic Switches � I
Genetic Switches � II
Biochemical, Genetics and Systems Biology Paradigms
Quorum Sensing � The Language of Bacteria
Quorum Sensing in Gram Negative and Gram Positive Bacteria
Hybrid Quorum Sensing in Vibrio harveyi � Two Component Signalling
Programmed Population Control by Cell �Cell Communication and Regulated Killing � I
Programmed Population Control by Cell �Cell Communication and Regulated Killing � II
Drosophila melanogaster � Life Cycle
Drosophila melanogaster � Morphogen Gradient
Establishment of Developmental Precision and Proportions in the Early Drosophila Embryo
Michaelis Menten Kinetics � Enzyme Binding and Cooperativity
Michaelis Menten Kinetics � I
Michaelis Menten Kinetics � Enzyme Inhibition
Michaelis Menten Kinetics � Identical Independent Binding Sites
Michaelis Menten Kinetics � Sequential Model of Cooperativity
Michaelis Menten Kinetics , Non Identical Interacting Binding Sites
Structure ad Genetic Map of Lambda Phage
The Classical Genetic Switch in Lambda Phage - Lytic and Lysogeny Decisions
Noise in Gene Expression
Quantifying Noise in Gene Expression
Noise in Gene Regulatory Networks
Noise based Switches and Amplifiers for Gene Expression
Bacterial Chemo taxis
The Signalling Pathway in Chemo taxis
Gene Expression Networks
Transcription Networks I
Transcription Networks II
Networks in Biology - Network Motifs
Feed Forward Loops in Biological Systems
Coherent Feed Forward Loops
Incoherent Feed Forward Loops
Kinetics of Coherent FFLs-Sign sensitive delay circuits
Kinetics of Incoherent FFLs-Sign sensitive accelerator circuits
Pathway Mapping through KEGG
Cytoscape
Virtual Cell
102103013
Biotechnology
Genetic Engineering & Applications
Dr. Utpal Bora
Web
IIT Guwahati
Select
Role of genes within cells, genetic code, genetic elements that control gene expression
Method of creating recombinant DNA molecules
Types, biology and salient features of vectors in recombinant DNA technology: Plasmids
Types, biology and salient features of vectors in recombinant DNA technology
Safety guidelines for recombinant DNA research
Control of spills and mechanism of implementation of biosafety guidelines
Enzymes in genetic engineering: Restriction nucleases: exo & endo nucleases
Enzymes in modification- Polynucleotide phosphorylase, DNase and their mechanism of action.
Enzymes in modification- Methylases and phosphatases and their mechanism of action.
Enzymes in modification- Polynucleotide kinase, Ligases, RNase and their mechanism of action.
Methods of nucleic acid detection.
Polymerase chain reaction (PCR) and its applications
Variations in PCR and their applications
Methods of nucleic acid hybridization
Probe and target sequences
Nucleic acid mutagenesis in vivo and in vitro
Isolation and purification of nucleic acid (genomic/plasmid DNA and RNA)
Quantification and storage of nucleic acids.
Construction of cDNA library
Construction of Genomic library
Screening and preservation of DNA libraries
Gene transfer techniques: biological methods
Gene transfer techniques: chemical methods
Gene transfer techniques: physical or mechanical methods
Agro- bacterium mediated gene transfer in plants
Chloroplast transformation
Transgenic science in plant improvement
Biopharming - plants as bioreactors
Transgenic science for animal improvement
Biopharming- Animals as bioreactor for recombinant protein
Gene mapping in plants and animals
Marker-assisted selection for plant breeding and livestock improvement
Microbial biotechnology: Genetic manipulation
Engineering microbes for the production of antibiotics and enzymes
Engineering microbes for the production of insulin, growth hormones, monoclonal antibodies
Engineering microbes for clearing oil spills
Gene therapy: Introduction and Methods
Gene targeting & silencing
Gene therapy in the treatment of diseases
Challenges & future of gene therapy
M1-Problems
M2-Problems
M3-Problems
M5-Problems
M6-Problems
M7-Problems
M8-Problems
DNA Sequencing and Cloning Stategies
M4-Problems
102106036
Biotechnology
Tissue Engineering
Dr. S. Swaminathan
Web
SASTRA University
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Introduction to Tissue Engineering
Cells as Therapeutic Agents
Cells as Therapeutic Agents.
Tissue Organization
Extracellular Matrix
Tissue Organization.
Cellular Fate Processes
Cellular Fate Processes.
Cell Division
Cell death – biological process of apoptosis
Coordination of cellular fate process
Coordination of cellular fate process.
Malfunctions in soluble signalling
How Cell-Extra cellular matrix interactions can co-ordinate cell fates?
Direct cell-cell contact
Bidirectional nature of cell-cell communication
Microscopic Characterization of Tissues and Biomaterials
Basic tools to detect cell fate and cell functions
Cell and Tissue Culture
Culture Environment and maintenance of cells in vitro
Cell separation
Biomaterials in tissue engineering
Scanning Electron Microscope
Biomaterials in tissue engineering.
Scaffold fabrication technologies and tailoring Biomaterials
Growth factor delivery
Stem cells
Stem cells and tissue engineering
Gene transfer
Gene transfer.
Gene transfer..
Bioreactors in tissue engineering
Artificial blood vessels
Artificial blood vessels.
Artificial pancreas
Artificial Pancreas.
Liver Tissue Engineering